Macrothrombocytopenia ( MTC-D )

Cavalier King Charles Spaniels

Toy Poodles

The Disease:

Macrothrombocytopenia ( MTC ) is inherited as an autosomal dominant trait.


Clinical Signs:

Characterized by low platelet count and the presence of some larger than normal platelets in circulation. Unlike acquired macrothrombocytopenia (thrombocytopenias secondary to infectious agents, medications, immune-mediated causes), this form does not respond to treatment. 

It is important to note that these dogs may mistakenly be considered to have an underlying disease that results in thrombocytopenia, such as immune-mediated thrombocytopenia, tick-borne infection, or a bone marrow disorder. 

2022: CameronCavs test for this condition.