Neonatal encephalopathy (NE / NEWS)

Toy Poodles

The Disease:

Neonatal encephalopathy with seizures is an autosomal recessive developmental brain disease.

 

Clinical Signs:

Affected puppies exhibit extreme weakness, those that survive the first week of life generally develop progressively worse ataxia and a whole-body tremor. This is often accompanied by severe generalized clonic-tonic seizures. None have survived to 7 weeks of age.

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